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KefenTech Plaster

hst3Background

Kefentech the sophisticated therapeutics for arthritis was developed By JEIL Pharmaceutical CO., LTD. in Korea and marketed by WooShin Medics, Co. to outside Korea. In Myanmar, Hnin Shwe Taung Co., Ltd Imports and distributes as authorized distributor. Kefentech is an effective and safe therapeutic plaster for arthritis   without systemic side effects like G.I. troubles, hepatotoxicity or nephrotoxicity, and prolonged effect by constant drug delivery is another uniqueness of Kefentech. The excellence of ketoprofen is already well known worldwide, Its effect and safety were innovated by new delivery system of Kefentech, the plaster for muscular pain, osteoarthritis and rheumatoid arthritis.

 

hst2GENERAL INFORMATIONS

hst31. ACTIVE INGREDIENT : Ketoprofen 30mg / 1 sheet   (7cm X 10cm ; 2.4g)

ketoprofen

 

* C16H14O3

* MW: 254.29

 

 

hst32. DIRECTIONS / DOSE : Twice daily, Apply to the sites of pain

(PK Data is shown 1’s patch per day)

 

hst33. INDICATIONS :

kefentech_plaster4* Arthritis deformans

* Rheumatoid arthritis

* Neuralgia

* Periarthritis humelo-scapularis

* Tendinitis

* Peritendinitis

* Tennis elbow

* Muscular pain

* Contusion, Distorsion

 

hst3ADVANTAGE:

hst3(1) Comparison between Ketoprofen TDS plaster and Ketoprofen orally administration

-- Ketoprofen TDS plaster can reduce systemic side effects such as gastric irritation or nephrotoxicity in every kind of orally administered NSAID.

-- Ketoprofen TDS plaster can attain constant drug delivery through skin which can reduce fluctuations in local drug concentrations, therefore can rapidly achieved effective tissue levels, as well as can attain higher drug concentration at local tissues such as muscle and joint with less systemic exposure to the drug.

 

hst3(2) Comparison between Ketoprofen TDS plaster and Ketoprofen gel

-- Compared with Ketoprofen plaster, it is difficult in controlling the applied area and the amount of drug on the skin when using Ketoprofen gel-type. This can cause serious fluctuation in drug concentration in the tissue.

-- Photosensitization Study of Kefentech plaster/Ketoprofen gel in Hartley guinea pigs showed: Kefentech plaster have no photosensitization potential in Guinea pigs. But Ketoprofen gel had a skin photosensitization potential in guinea pigs under the study conditions. The photosensitization potential of the test article was classified as grade III.

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